Skylanders Imaginators Yuzu -

I understand you're asking about running Skylanders: Imaginators on the emulator (Nintendo Switch emulation for PC/Android).

Playable (with major caveats) on Yuzu (Mainline/Early Access builds) and its fork Suyu (since Yuzu development was discontinued). skylanders imaginators yuzu

Here's a direct, factual answer based on the current emulation status: skylanders imaginators yuzu